Rapid identification of a Leptotrichia trevisanii catheter-related bloodstream infection using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Issue 4 (31st August 2015)

• Record Type: Journal Article
• Authors: Martín-Gutiérrez, Guillermo; Rodríguez, Nancy; Lepe, José Antonio; Parody, Rocío; Torres, María José; Aznar, Javier
• Is Part Of: JMM case reports. Volume 2:Issue 4(2015)
• Publication Date: 2015-08-31
• Subjects: catheter-related infection -- Leptotrichia trevisanii -- MALDI-TOF; Medical microbiology -- Periodicals; 616.9041
• DOI: 10.1099/jmmcr.0.000036
• Languages: English
• ISSNs: 2053-3721

Abstract

Abstract : Introduction: Leptotrichia trevisanii is a large, fusiform, non-sporulating, motile, Gram-negative rod, and is a member of the family Fusobacteriaceae in the phylum Fusobacteria . Although L. trevisanii bacteraemia is extremely rare, severe infections have been reported in immunocompromised patients. Case presentation: We present a case of a 69-year-old woman diagnosed with diffuse large B-cell lymphoma, who suffered a catheter-related bloodstream infection due to L. trevisanii during the post-autologous peripheral blood progenitor-cell transplantation aplasia phase. In this case, rapid identification of the opportunistic pathogen was achieved using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry directly from a blood culture, with correct identification of the micro-organism within 2 h after the blood culture became positive. Conclusion: Rapid identification of this opportunistic pathogen allowed initiation of appropriate antimicrobial therapy, which contributed to a successful clinical outcome for the patient.