Longitudinal Research at the Interface of Affective Neuroscience, Developmental Psychopathology, Health and Behavioral Genetics: Findings from the Wisconsin Twin Project. (August 2019)

• Record Type: Journal Article
• Authors: Schmidt, Nicole L.; Brooker, Rebecca J.; Carroll, Ian C.; Gagne, Jeffrey R.; Luo, Zhan; Planalp, Elizabeth M.; Sarkisian, Katherine L.; Schmidt, Cory K.; Van Hulle, Carol A.; Lemery-Chalfant, Kathryn; Goldsmith, H. H.
• Is Part Of: Twin research and human genetics. Volume 22:Number 4(2019)
• Page Start: 233
• Page End: 239
• Publication Date: 2019-08
• Subjects: twins, -- longitudinal, -- temperament, -- developmental psychopathology, -- neuroimaging, -- sensory, -- behavior genetics; Twins -- Periodicals; Multiple birth -- Periodicals; 618.25
• DOI: 10.1017/thg.2019.55
• Languages: English
• ISSNs: 1832-4274

Abstract

Abstract: The Wisconsin Twin Project comprises multiple longitudinal studies that span infancy to early adulthood. We summarize recent papers that show how twin designs with deep phenotyping, including biological measures, can inform questions about phenotypic structure, etiology, comorbidity, heterogeneity, and gene–environment interplay of temperamental constructs and mental and physical health conditions of children and adolescents. The general framework for investigations begins with rich characterization of early temperament and follows with study of experiences and exposures across childhood and adolescence. Many studies incorporate neuroimaging and hormone assays.