Effectiveness of oral appliances versus continuous positive airway pressure in treatment of OSA patients: An updated meta-analysis. Issue 6 (2nd November 2019)

• Record Type: Journal Article
• Authors: Zhang, Menghan; Liu, Yuehua; Liu, Yuanshun; Yu, Fengyang; Yan, Shaowen; Chen, Lulu; Lv, Chenxing; Lu, Haiping
• Is Part Of: Cranio. Volume 37:Issue 6(2019)
• Page Start: 347
• Page End: 364
• Publication Date: 2019-11-02
• Subjects: Meta-analysis -- obstructive sleep apnea -- oral appliance -- continuous positive airway pressure; Temporomandibular joint disorders -- periodicals; Temporomandibular joint -- Diseases -- Periodicals; 617.51
• DOI: 10.1080/08869634.2018.1475278
• Languages: English
• ISSNs: 0886-9634

Abstract

Abstract: Objective: To update the meta-analysis comparing the effectiveness of oral appliance (OA) with continuous positive airway pressure (CPAP) in treating patients with obstructive sleep apnea (OSA). Methods: PubMed, ISI Web of Knowledge, Ovid, EBSCO Dentistry & Oral Science Source, The Cochrane Library, and Embase database were searched for RCTs until 23 May 2017. Meta-analyses were performed using RevMan 5.3. Results: Sixteen RCTs were included. Compared with OA, CPAP significantly decreased AHI, min SaO2, ARI, ESS ( p < 0.05), with no significant difference in REM%, FOSQ, BP ( p ≥ 0.05). OA significantly improved REM% in the severe groups and ESS in the adjustable OA group ( p < 0.05). OA shared greater preference. Conclusion: Even though CPAP can better decrease the severity of OSA, more patients opted for OA, which showed better results in severe patients, especially adjustable OA.