Catalytic Asymmetric Syntheses of 2‐Aryl Chromenes. Issue 10 (12th August 2019)

• Record Type: Journal Article
• Authors: Yang, Qingjing; Guo, Rui; Wang, Jun (Joelle)
• Is Part Of: Asian journal of organic chemistry. Volume 8:Issue 10(2019)
• Page Start: 1742
• Page End: 1765
• Publication Date: 2019-08-12
• Subjects: asymmetric synthesis -- flavenes -- heterocycles -- flavanones -- chromene; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.201900360
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract: Chiral chromene motifs are important heterocycles in numerous natural products and bioactive molecules. Among them, flavenes, flavanes, and flavanones, which consist of the 2‐aryl‐chromene skeleton are observed most frequently. As subgroups of flavonoids, they often occur in various plants and show many biological activities, such as antitumor, antioxidant, antibacterial, anti‐inflammatory, and anticoagulant properties. This Minireview summarizes recent reports on catalytic asymmetric synthesis of flavenes, flavanes, and flavanones. Abstract : Good flava : Chiral chromene motifs are important heterocycles in numerous natural products and bioactive molecules. Among them, flavenes, flavanes and flavanones which consist the 2‐aryl‐chromene skeleton are observed most frequently. As subgroups of flavonoids, they often occur in various plants and show many biological activities, such as antitumor, antioxidant, antibacterial, anti‐inflammatory, and anticoagulation properties. This Minireview summarizes recent reports on catalytic asymmetric synthesis of flavenes, flavanes, and flavanones.