Electrochemical Oxidative C−H Sulfonylation of Anilines. Issue 10 (20th August 2019)

• Record Type: Journal Article
• Authors: Lu, Fangling; Li, Jun; Wang, Tao; Li, Zhen; Jiang, Minbao; Hu, Xingxing; Pei, Hongqiao; Yuan, Feng; Lu, Lijun; Lei, Aiwen
• Is Part Of: Asian journal of organic chemistry. Volume 8:Issue 10(2019)
• Page Start: 1838
• Page End: 1841
• Publication Date: 2019-08-20
• Subjects: sulfones -- sulfonylation -- C−H activation -- radical reactions -- electrochemistry; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.201900447
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract: An electrochemical oxidative C−H sulfonylation of anilines without a metal catalyst and an external oxidant has been developed. Various sodium sulfinates are compatible, generating the desired products in up to 96% yield. Preliminary mechanism studies suggest that a radical cross‐coupling process is involved in this transformation. Abstract : Electric atmosphere : An efficient and environmentally friendly electrosynthesis of aryl sulfones via electrochemical oxidative C−H sulfonylation of anilines under metal‐free and external‐oxidant‐free conditions has been developed. A broad range of sodium sulfonates and anilines were compatible, and the reaction could be conducted on gram scale with high reaction efficiency.