Pre-existing medical disorders as risk factors for preeclampsia: an exploratory case-control study. (2nd October 2019)

• Record Type: Journal Article
• Authors: Pan, Linglan; Fu, Zhen; Yin, Ping; Chen, Dunjin
• Is Part Of: Hypertension in pregnancy. Volume 38:Number 4(2019)
• Page Start: 245
• Page End: 251
• Publication Date: 2019-10-02
• Subjects: Preeclampsia -- pre-existing medical disorder -- risk factors -- case-control study; Hypertension in pregnancy -- Periodicals; Pregnancy -- Complications -- Periodicals; 618.3261
• DOI: 10.1080/10641955.2019.1667381
• Languages: English
• ISSNs: 1064-1955

Abstract

ABSTRACT: Objective : We sought to explore pre-existing medical disorders as risk factors for preeclampsia as thoroughly as possible. Methods : A case-control design. A group of 1, 652 patients were identified as the preeclampsia group, and another randomly selected 4, 500 patients were identified as the non-preeclampsia group. Results : Mature ovarian teratoma (adjusted odds ratio [OR] 7.69, 95% CI 1.58–37.53), uterine fibroids (adjusted OR 2.24, 95% CI 1.28–3.92) and pregestational hypothyroidism (adjusted OR 5.17, 95% CI 2.43–11.00), were significantly correlated with preeclampsia. Conclusions : Mature ovarian teratoma, uterine fibroids and pregestational hypothyroidism may also contribute to the incidence of preeclampsia.