Asperfurandiones A and B, two antifungal furandione analogs from a marine-derived fungus Aspergillus versicolor. Issue 23 (2nd December 2019)

• Record Type: Journal Article
• Authors: Ding, Lijian; Xu, Peng; Li, Te; Liao, Xiaojian; He, Shan; Xu, Shihai
• Is Part Of: Natural product research. Volume 33:Issue 23(2019)
• Page Start: 3404
• Page End: 3408
• Publication Date: 2019-12-02
• Subjects: Marine-derived fungi -- Aspergillus versicolor -- furandione -- antifungal activity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2018.1480622
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Two new furandione derivatives, designated as asperfurandiones A (1 ) and B (2 ), were isolated from the solid culture of the marine-derived fungus Aspergillus versicolor . Their structures were elucidated using a combination of mass spectrometry and NMR spectroscopy. Additionally, asperfurandiones A and B both showed moderate antifungal activity against Gaeumannomyces graminis, Cryptococcus neoformans, and Candida albicans with MIC values of 64 μg/mL. Abstract :