A phytochemical study of the Cuphea glutinosa from Southern Brazil: Na+, K+-ATPase activity inhibition and antioxidant properties. Issue 23 (2nd December 2019)

• Record Type: Journal Article
• Authors: Zago, Adriana M.; Carvalho, Fabiano B.; Gutierres, Jessié Martins; Bohnert, Crystiani; Fernandes, Marilda da Cruz; Morandini, Liziane M.; Coelho, Helena S.; Fogaça, Aline O.; Andrade, Cinthia M.; Mostardeiro, Marco A.; Dalcol, Ionara I.; Morel, Ademir F.
• Is Part Of: Natural product research. Volume 33:Issue 23(2019)
• Page Start: 3426
• Page End: 3431
• Publication Date: 2019-12-02
• Subjects: Cuphea glutinosa -- phytochemistry -- scavenger properties -- Na+, K+-ATPase; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2018.1477143
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: This study investigated the antioxidant activity of Cuphea glutinosa (CG) and its effect on Na +, K + -ATPase from cardiac muscle . The ethanolic extract showed higher antioxidant capacity compared to aqueous and ethyl acetate fraction. Ethyl acetate fraction showed β-sitosterol-3-O-β-glucoside, kaempferol, quercetin, isoquercetin, gallic acid methyl ester, and gallic acid. The ethanolic extract also reduced the Na +, K + -ATPase activity. CG presented a promising antioxidant activity and inhibitory effect on the Na +, K + -ATPase activity, supporting biochemical evidences the popular use of this plant in the treatment of heart failure. Abstract :