The Association Between Tea Consumption and Hyperhomocysteine in Chinese Hypertensive Patients. (31st October 2018)

• Record Type: Journal Article
• Authors: Zhu, Jun; Wang, Wei; Xiong, Yaqing; Cooper, Richard S; Du raza-Arvizu, Ramon; Cao, Guichan; Wang, Yi; Ji, Peng; Bian, Rongwen; Xu, Jiaren
• Is Part Of: American journal of hypertension. Volume 32:Number 2(2019)
• Page Start: 209
• Page End: 215
• Publication Date: 2018-10-31
• Subjects: blood pressure -- hyperhomocysteine -- hypertension -- tea-drinking; Hypertension -- Periodicals; 616.132005
• DOI: 10.1093/ajh/hpy163
• Languages: English
• ISSNs: 0895-7061

Abstract

Abstract: BACKGROUND: There is no consistent evidence for the relationship between tea-drinking and hyperhomocysteine (hHcy). Because tea-drinking habit and hHcy have prevailed in Chinese hypertensive patients, this study aimed to investigate the association between hHcy and tea consumption in patients with hypertension. METHODS: A total of 335 hypertensive participants were recruited from 7 communities. Demographic characteristics of participants were collected through face-to-face interviews using a standard questionnaire, whereas laboratory data were obtained within 1 week after patient recruitment. Multiple logistic regression analysis was performed to examine the association between tea consumption and hHcy in hypertensive patients. RESULTS: Of the 335 patients, 245 had a tea-drinking habit, and 252 of them were detected with hHcy. A significant association was found between tea consumption and hHcy in hypertensive patients (adjusted odds ratio [OR] = 1.84, 95% confidence interval [CI] = 1.01–3.36, P = 0.048). Subgroup analyses showed that black tea drinking group (adjusted OR = 8.81, 95% CI = 2.74–28.33, P < 0.001) was significantly associated with the risk of hHcy, but not oolong and green tea drinking groups ( P > 0.05). Furthermore, consuming a small amount (≤1 cup per day) of green tea was negatively associated with hHcy (adjusted OR = 0.19, 95% CI = 0.07–0.51, P = 0.001), whereas a large intake (>3 cups per day) of green tea was associated with high odds of hHcy (adjusted OR = 5.00, 95% CI = 1.33–18.79, P = 0.02). CONCLUSIONS: These data suggest a hypothesis that selecting green tea or limiting tea consumption might reduce risk of hHcy in hypertensive patients and that warrants further study.