Mosquito-borne epornitic flaviviruses: an update and review. (22nd January 2019)

• Record Type: Journal Article
• Authors: Benzarti, Emna; Linden, Annick; Desmecht, Daniel; Garigliany, Mutien
• Is Part Of: Journal of general virology. Volume 100:Number 2(2019)
• Page Start: 119
• Page End: 132
• Publication Date: 2019-01-22
• Subjects: birds -- flaviviruses -- epornitic -- mosquitoes -- vaccine; Virology -- Periodicals; Viruses; Microbiology; Virology; Virologie -- Périodiques; Microbiologie -- Périodiques; Virology; Virologie; Virologie; Electronic journals; Periodical; Periodicals; 579.2
• DOI: 10.1099/jgv.0.001203
• Languages: English
• ISSNs: 0022-1317

Abstract

Abstract : West Nile Virus, Usutu virus, Bagaza virus, Israel turkey encephalitis virus and Tembusu virus currently constitute the five flaviviruses transmitted by mosquito bites with a marked pathogenicity for birds. They have been identified as the causative agents of severe neurological symptoms, drop in egg production and/or mortalities among avian hosts. They have also recently shown an expansion of their geographic distribution and/or a rise in cases of human infection. This paper is the first up-to-date review of the pathology of these flaviviruses in birds, with a special emphasis on the difference in susceptibility among avian species, in order to understand the specificity of the host spectrum of each of these viruses. Furthermore, given the lack of a clear prophylactic approach against these viruses in birds, a meta-analysis of vaccination trials conducted to date on these animals is given to constitute a solid platform from which designing future studies.