Urethral diverticular with broadly squamous metaplasia in a patient with urethral diverticular calculi: A case report. Issue 34 (August 2019)

• Record Type: Journal Article
• Authors: Sun, Yi; Tang, Cai; Bai, Yun-jin; Li, Na; Yang, Lu; Wei, Qiang; Wei, Xin; Shen, Hong
• Other Names: NA. section editor.
• Is Part Of: Medicine. Volume 98:Issue 34(2019)
• Publication Date: 2019-08
• Subjects: broadly squamous metaplasia -- calculi -- urethral diverticular; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000016923
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Rationale: There are already several reports concerning the occurrence of urethral diverticulum (UD) in female patients, but only rarely has a article describing UD combined with UD calculi or squamous carcinoma been published. Moreover, a case with squamous carcinoma and UD calculi at the same time has never been reported, making this the first case report about this condition. Patient concerns: A 43-year-old woman presented to the gynaecology department with a complaint of a hard mass beneath the anterior vaginal wall. Diagnoses: Transvaginal ultrasound (TVU) revealed a UD. Interventions: We performed a standard urethral diverticular excision. Intraoperatively, we identified and removed a stone from the diverticulum. The intraoperative finding of a stone challenged the diagnosis of UD, with subsequent histological examination of biopsy tissue from the mass demonstrating broadly squamous metaplasia. Outcomes: The broadly squamous metaplasia predominantly originated from the stone, and the stone was entirely removed. No complications occurred during the whole follow-up period. Moreover, after the 12-month follow-up, there was no diverticular recurrence or carcinoma metastasis. Lessons: UD calculi may be considered a risk factor for female urethra squamous metaplasia, which with the potential of squamous carcinoma, so patients will be advised to treat this condition immediately.