Air‐Induced One‐Pot Synthesis of N‐Sulfonylformamidines from Sulfonyl Chlorides, NaN3, and Tertiary/Secondary Amines. Issue 35 (4th September 2019)

• Record Type: Journal Article
• Authors: Bi, Wen‐Zhu; Zhang, Wen‐Jie; Li, Zi‐Jie; Xia, Xiao‐Yi; Chen, Xiao‐Lan; Qu, Ling‐Bo; Zhao, Yu‐Fen
• Is Part Of: European journal of organic chemistry. Issue 35(2019)
• Page Start: 6071
• Page End: 6076
• Publication Date: 2019-09-04
• Subjects: Homogeneous catalysis -- Multicomponent reactions -- Sulfonamides -- Synthetic methods; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201901048
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : An efficient and practical one‐pot strategy for the synthesis of N ‐sulfonylformamidines was developed by directly using easily available sulfonyl chlorides, sodium azide and tertiary/secondary amines in the presence of 5 mol‐% CuBr2 under aerobic oxidative conditions. Abstract : Several of N ‐sulfonylformamidines were synthesized in one‐pot using easily available sulfonyl chlorides, sodium azide and tertiary/secondary amines in the presence of 5 mol‐% CuBr2 in DCE under aerobic oxidative conditions.