Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection. Issue 5 (October 2016)

• Record Type: Journal Article
• Authors: Mac Aogáin, Micheál; Miajlovic, Helen; Moloney, Geraldine; Chotirmall, Sanjay H.; Rogers, Thomas R.; Smith, Stephen G. J.
• Is Part Of: JMM case reports. Volume 3:Issue 5(2016)
• Publication Date: 2016-10
• Subjects: Pyelonephritis -- bacteraemia -- Escherichia coli ST-458 -- Virulence factors -- Antimicrobial resistance -- Infected renal parenchymal cyst; Medical microbiology -- Periodicals; 616.9041
• DOI: 10.1099/jmmcr.0.005061
• Languages: English
• ISSNs: 2053-3721

Abstract

Abstract : Introduction: Globally, extra-intestinal pathogenic Escherichia coli are one of the predominant causative agents of bacteraemia. Case presentation: This case report outlines a presentation of community-acquired pyelonephritis and secondary bloodstream infection in an 81-year-old man. Laboratory investigations revealed that the causative isolate was a multi-drug-resistant E. coli of a novel multi-locus sequence type. This sequence type (ST) was designated ST-458 and was most closely related to the globally prevalent ST-131 lineage. Conclusion: This is the first report of a novel E. coli ST, ST-458, which caused pyelonephritis and bacteraemia.