Aspergillus fumigatus native valve infective endocarditis in an otherwise healthy adult. Issue 2 (18th February 2016)

• Record Type: Journal Article
• Authors: Ikediobi, Uchenna; Sutton, Richard E.
• Is Part Of: JMM case reports. Volume 3:Issue 2(2016)
• Publication Date: 2016-02-18
• Subjects: Aspergillus fumigatus -- fungal endocarditis -- native valve endocarditis; Medical microbiology -- Periodicals; 616.9041
• DOI: 10.1099/jmmcr.0.005018
• Languages: English
• ISSNs: 2053-3721

Abstract

Abstract : Introduction: Fungal endocarditis is a rare cause of infective endocarditis, and Aspergillus spp. account for up to 30 % of all cases. Risk factors include intravenous drug use, immunosuppression, malignancy and the presence of prosthetic valves. Case presentation: We present a case of A. fumigatus endocarditis in a patient without any known or described risk factors. Conclusion: Diagnosis of Aspergillus endocarditis requires a high clinical index of suspicion, given the initial non-specific presentation, and treatment may require both medical and surgical therapies to ensure improved outcomes, but mortality rates still approach 80 %. Voriconazole remains the antifungal agent of choice.