Antimicrobial-resistant Gram-negative colonization in infants from a neonatal intensive care unit in Thailand. Issue 2 (October 2019)

• Record Type: Journal Article
• Authors: Roberts, T.; Limmathurotsakul, D.; Turner, P.; Day, N.P.J.; Vandepitte, W.P.; Cooper, B.S.
• Is Part Of: Journal of hospital infection. Volume 103:Issue 2(2019)
• Page Start: 151
• Page End: 155
• Publication Date: 2019-10
• Subjects: Extended-spectrum beta-lactamase -- Carbapenem resistance -- Antimicrobial resistance -- Neonate -- Colonization; Cross infection -- Periodicals; Cross infection -- Prevention -- Periodicals; Nosocomial infections -- Periodicals; Nosocomial infections -- Prevention -- Periodicals; Cross Infection -- Periodicals; Cross Infection -- prevention & control -- Periodicals; Infection Control -- Periodicals; Electronic journals; 614.44
• DOI: 10.1016/j.jhin.2019.04.004
• Languages: English
• ISSNs: 0195-6701

Abstract

Summary: Antimicrobial-resistant Gram-negative bacteria are a major cause of morbidity and mortality in hospitalized neonates in South and South-East Asia. This study aimed to determine the dynamics of colonization with antimicrobial-resistant Gram-negative bacteria amongst patients in a neonatal intensive care unit (NICU) in Thailand. From 97 enrolled patients, 52% were colonized by an extended-spectrum β-lactamase (ESBL) organism at some point during their stay and 64% were colonized by a carbapenem-resistant organism. Rapid acquisition of ESBL-positive and carbapenem-resistant organisms was found. Once colonized with an antibiotic-resistant organism, patients remained colonized for the remainder of their NICU stay.