Intra-aortic balloon pump and survival with favorable neurological outcome after out-of-hospital cardiac arrest: A multicenter, prospective propensity score-matched study. (October 2019)

• Record Type: Journal Article
• Authors: Kishimori, Takefumi; Matsuyama, Tasuku; Yamada, Tomoki; Hayakawa, Koichi; Yoshiya, Kazuhisa; Irisawa, Taro; Noguchi, Kazuo; Nishimura, Tetsuro; Uejima, Toshifumi; Yagi, Yoshiki; Kiguchi, Takeyuki; Kishimoto, Masafumi; Matsuura, Makoto; Hayashi, Yasuyuki; Sogabe, Taku; Morooka, Takaya; Sado, Junya; Shida, Haruka; Kiyohara, Kosuke; Shimazu, Takeshi; Kawamura, Takashi; Iwami, Taku; Kitamura, Tetsuhisa
• Is Part Of: Resuscitation. Volume 143(2019)
• Page Start: 165
• Page End: 172
• Publication Date: 2019-10
• Subjects: Out-of-hospital cardiac arrest -- Intra-aortic balloon pump -- Percutaneous mechanical circulatory support -- Post-Cardiac arrest syndrome; Resuscitation -- Periodicals; Resuscitation -- Periodicals; Réanimation -- Périodiques; Electronic journals; 616.025
• DOI: 10.1016/j.resuscitation.2019.07.002
• Languages: English
• ISSNs: 0300-9572

Abstract

Abstract: Objectives: This study aimed to evaluate whether intra-aortic balloon pump (IABP) use in nontraumatic out-of-hospital cardiac arrest (OHCA) patients who achieved return of spontaneous circulation (ROSC) is associated with favorable neurological outcome after OHCA. Background: The association between the IABP use in OHCA patients and favorable neurological outcome has not been extensively evaluated. Methods: The Comprehensive Registry of Intensive Cares for OHCA Survival (CRITICAL) study, a multicenter, prospective observational registry in Osaka, Japan, included consecutive nontraumatic OHCA patients aged ≥18 years who achieved ROSC from July 2012 to December 2016. The primary outcome was 1-month survival with favorable neurological outcome. Logistic regression analysis was used to evaluate the association between the IABP use or non-IABP use and favorable neurological outcome using one-to-one propensity score (PS) matching analysis. Results: Among the 2894 eligible patients, 10.4% used IABP, and 89.6% did not use IABP. In all patients, the proportion of 1-month survival with favorable neurological outcome was higher in the IABP use group than in the non-IABP use group (30.7% [92/300] vs. 13.2% [342/2594]). However, in PS-matched patients, the proportions of 1-month survival with favorable neurological outcome were almost consistent, and there were no significant differences between the IABP use group and the non-IABP use group (37.3% [59/158] vs. 41.1% [65/158]; adjusted odds ratio, 0.97; 95% confidence interval, 0.48–1.96). Conclusions: In this population, the current PS matching analysis did not reveal any association between the IABP use and 1-month survival with favorable neurological outcome among adult patients with ROSC after OHCA.