Prenatal exposure to endocrine-disrupting chemicals and child behavior. (August 2019)

• Record Type: Journal Article
• Authors: Toft, Gunnar; Høyer, Birgit Bjerre
• Is Part Of: Current opinion in endocrine and metabolic research. Volume 7(2019)
• Page Start: 43
• Page End: 48
• Publication Date: 2019-08
• Subjects: Prenatal exposure -- Behavior -- Bisphenol A -- Phthalates -- Perfluoralkyl substances -- Organochlorines; EDC Endocrine-disrupting chemicals -- PFAS Perfluoralkyl substances -- ADHD Attention-deficit hyperactivity disorder -- POP Persistent organic pollutants -- PCB Polychlorinated biphenyls -- DDT Dichlorodiphenyltrichloroethane -- DDE Dichlorodiphenyldichloroethylene -- PBDE Polybrominated diphenyl ethers -- BPA Bisphenol A -- CBCL Child Behavior Checklist -- SDQ Strength and Difficulties Questionnaire -- BASC-2 Behavior Assessment System for Children-2 -- K-SCQ Korean version of the Social Communication Questionnaire -- SRS-2 Social Responsiveness Scale-2 -- ICD-10 International Classification of Diseases and Related Health Problems, 10th edition -- DSM-IV Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition DSM–IV -- DEHP Diethylhexyl phthalate -- PFOA Perfluorooctaoic acid -- PFOS Perfluorooctane sulfonate -- PFHxS Perfluorohexane sulfonic acid -- PFHpA Perfluoroheptanoic acid -- PFNA Perfluorononanoic acid -- PFDA Perfluorodecanic acid; Endocrine glands -- Diseases -- Periodicals; Metabolism -- Disorders -- Periodicals; Endocrine System Diseases; Metabolic Diseases; Endocrine glands -- Diseases; Metabolism -- Disorders; Periodical; Electronic journals; Periodicals; Electronic journals; 616.4
• DOI: 10.1016/j.coemr.2019.06.008
• Languages: English
• ISSNs: 2451-9650

Abstract

Abstract: The potential adverse effects of prenatal exposure to endocrine-disrupting chemicals (EDCs) on child behavior have been addressed in several recent studies, and a review of 14 studies published in the last 2 years (March 2017–March 2019) is provided. The published studies are focusing on several classes of EDCs including bisphenol A, phthalates, organochlorines, perfluoralkyl substances (PFAS), and polybrominated diphenyl ethers (PBDEs). Several methods have been used to identify abnormal behavior, including questionnaires and registered diagnoses. Overall, the results indicate that abnormal behavior may be associated with several of the EDC exposures although not entirely consistent. The most convincing associations observed relate to phthalate exposures (four studies all showing adverse associations) and PFAS exposures where both studies included also indicated an adverse association.