Isolation of Nontuberculous Mycobacteria in Southeast Asian and African Human Immunodeficiency Virus–infected Children With Suspected Tuberculosis. (28th January 2019)

• Record Type: Journal Article
• Authors: Borand, Laurence; de Lauzanne, Agathe; Nguyen, Ngoc Lan; Cheng, Sokleaph; Pham, Thu Hang; Eyangoh, Sara; Ouedraogo, Abdoul-Salam; Ung, Vibol; Msellati, Philippe; Tejiokem, Mathurin; Nacro, Boubacar; Inghammar, Malin; Dim, Bunnet; Delacourt, Christophe; Godreuil, Sylvain; Blanche, Stéphane; Marcy, Olivier
• Is Part Of: Clinical infectious diseases. Volume 68:Number 10(2019)
• Page Start: 1750
• Page End: 1753
• Publication Date: 2019-01-28
• Subjects: HIV -- children -- nontuberculous mycobacteria -- tuberculosis; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciy897
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: : We enrolled 427 human immunodeficiency virus–infected children (median age, 7.3 years), 59.2% severely immunodeficient, with suspected tuberculosis in Southeast Asian and African settings. Nontuberculous mycobacteria were isolated in 46 children (10.8%); 45.7% of isolates were Mycobacterium avium complex. Southeast Asian origin, age 5–9 years, and severe immunodeficiency were independently associated with nontuberculous mycobacteria isolation. Clinical Trials Registration: NCT01331811.