The usefulness of narrow-band imaging for the diagnosis and treatment of vocal fold leukoplakia. (2nd September 2017)

• Record Type: Journal Article
• Authors: Huang, Fang; Yu, Jinchao; Zhang, Fan; He, Changding; Li, Shimin; Shao, Jun
• Is Part Of: Acta oto-laryngologica. Volume 137:Number 9(2017)
• Page Start: 1002
• Page End: 1006
• Publication Date: 2017-09-02
• Subjects: Leukoplakia -- vocal fold -- narrow-band imaging -- dysplasia -- carcinoma; Otolaryngology -- Periodicals; Ear -- Diseases -- Periodicals; Throat -- Diseases -- Periodicals; Otolaryngology -- Electronic Resources; Otorhinolaryngologic Diseases; 617.8
• DOI: 10.1080/00016489.2017.1324216
• Languages: English
• ISSNs: 0001-6489

Abstract

Abstract: Objective: This research was aimed to explore the efficacy of narrow-band imaging (NBI) on distinguishing the degree of dysplasia of vocal fold leukoplakia. Methods: Patients were examined by flexible endoscopy, under white light endoscopy (WLE) and NBI. 78 lesions were divided into two groups according to the NBI classification. Group 1: non-dysplasia (ND), including squamous hyperplasia with hyperkeratosis or parakeratosis; Group 2: squamous hyperplasia with mild or moderate dysplasia (MD) or severe dysplasia (SD), or carcinoma in situ (CIS). Results: The diagnostic accuracy of NBI for Group 1 and Group 2 was 69.70% (23/33) and 95.56% (43/45), respectively, and the kappa index was 0.711 and a p value < .05, which was considered statistically significant. Conclusions: The NBI could roughly estimate the degree of dysplasia. Differentiating between ND, MD, SD, and CIS, which may be useful for clinicians on selecting suitable therapies.