Cardiovascular Risk Factor Reduction in First Responders Resulting From an Individualized Lifestyle and Blood Test Program: A Randomized Controlled Trial. Issue 3 (March 2019)

• Record Type: Journal Article
• Authors: Gill, Rosalynn; Superko, Harold Robert; McCarthy, Megan M.; Jack, Kepra; Jones, Briana; Ghosh, Debanjali; Richards, Steve; Gleason, Joi A.; Williams, Paul T.; Dansinger, Michael
• Is Part Of: Journal of occupational and environmental medicine. Volume 61:Issue 3(2019)
• Publication Date: 2019-03
• Subjects: coronary heart disease -- diet -- firefighters -- high density lipoprotein-cholesterol -- high density lipoprotein -- lifestyle -- police officers -- risk modification; Medicine, Industrial -- Periodicals; Environmental health -- Periodicals; Occupational Medicine -- Periodicals; Environmental Medicine -- Periodicals; Environmental health; Medicine, Industrial; Periodicals; Electronic journals; 616.9803
• DOI: 10.1097/JOM.0000000000001490
• Languages: English
• ISSNs: 1076-2752

Abstract

Abstract : Objective: We tested the hypothesis that a lifestyle program would improve risk factors linked to cardiovascular disease (CVD) in first responders. Methods: A 1-year cluster-randomized controlled clinical trial in 10 cities. Participants were 175 first responders, with increased waist circumference and/or low levels of large ( α 1 ) high-density lipoprotein (HDL) particles. The intervention group received personalized online tools and access to telephonic coaching sessions. Results: At 1 year the intervention significantly reduced body weight ( P = 0.004) and waist circumference ( P = 0.002), increased α 1 HDL ( P = 0.01), and decreased triglyceride ( P = 0.005) and insulin concentrations ( P = 0.03). Program adherence was associated with weight loss ( P = 0.0005) and increases in α1 HDL ( P = 0.03). Conclusions: In first responders, a personalized lifestyle intervention significantly improved CVD risk factors in proportion to program adherence. Changes in large HDL particles were more sensitive indicators of lifestyle changes than HDL-cholesterol measurement. Clinical Trial Registration Number: ClinicalTrials.gov: NCT03322046 Abstract : Supplemental Digital Content is available in the text