Whole-Body Staging of Metastatic Atypical Meningioma Using 68Ga-DOTATATE PET/CT. (March 2019)

• Record Type: Journal Article
• Authors: Unterrainer, Marcus; Ilhan, Harun; Vettermann, Franziska; Cyran, Clemens C.; Tonn, Joerg C.; Niyazi, Maximilian; Bartenstein, Peter; Albert, Nathalie L.
• Is Part Of: Clinical nuclear medicine. Volume 44:Number 3(2019)
• Publication Date: 2019-03
• Subjects: atypical meningioma -- DOTATATE -- meningioma -- metastases; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002422
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 43-year-old woman with suspected recurrence of atypical meningioma World Health Organization grade II presented extensive intracranial lesions with high 68 Ga-DOTATATE uptake. Moreover, numerous 68 Ga-DOTATATE–positive bone, lung, and liver lesions were seen. For final diagnosis, biopsies taken from a lung lesion revealed distant metastases of the atypical meningioma. This case underlines the high diagnostic power of 68 Ga-DOTATATE PET/CT for the staging of meningioma even beyond cerebral or spinal lesions; in case of distant lesions in patients with known meningioma, differential diagnosis should also contain metastases despite their rare occurrence. Moreover, this case emphasizes radioligand therapy especially in metastatic meningioma.