Corneal Higher-Order Aberrations in Eyes With Corneal Scar After Traumatic Perforation. Issue 2 (March 2019)

• Record Type: Journal Article
• Authors: Shimizu, Eisuke; Yamaguchi, Takefumi; Tsubota, Kazuo; Shimazaki, Jun
• Is Part Of: Eye & contact lens. Volume 45:Issue 2(2019)
• Publication Date: 2019-03
• Subjects: Higher-order aberration -- Corneal scar -- Traumatic perforation -- Visual acuity -- Irregular astigmatism; Contact lenses -- Periodicals; Intraocular lenses -- Periodicals; Orthokeratology -- Periodicals; Anterior segment (Eye) -- Diseases -- Periodicals; 617.7523
• DOI: 10.1097/ICL.0000000000000530
• Languages: English
• ISSNs: 1542-2321

Abstract

Abstract : Objectives: To evaluate corneal higher-order aberrations (HOAs) in eyes with corneal scar after traumatic perforation and their correlation with visual acuity. Methods: This retrospective consecutive case study included 40 eyes of 40 consecutive patients (mean age, 39.2±21.6 years), treated for traumatic corneal perforation at Tokyo Dental College, and 18 normal control eyes. Higher-order aberrations of anterior and posterior corneal surfaces and total cornea were analyzed by swept-source optical coherence tomography. Correlations between corneal HOAs and visual acuity were analyzed. Results: Higher-order aberrations within 4-mm diameter were significantly larger in eyes with corneal perforation (anterior surface, 0.51±0.54 μm; posterior surface, 0.20±0.14; and total cornea, 0.52±0.50) as compared to normal controls (0.10±0.02, 0.02±0.01, and 0.09±0.02, respectively; all P <0.001). Higher-order aberrations within 6-mm diameter were significantly larger in eyes with corneal perforation (anterior surface, 1.15±1.31; posterior surface, 0.31±0.23; and total cornea, 1.09±1.28) as compared to normal controls (0.21±0.06, 0.06±0.01, and 0.19±0.06, respectively; all P <0.001). The most common topography pattern observed was the minimal change pattern (37.5%), followed by asymmetric pattern (30.0%). Visual acuity significantly correlated with corneal HOAs (anterior surface: R =0.646, P <0.001; posterior surface: R =0.400, P =0.033; and total cornea: R =0.614, P <0.001). Conclusions: Corneal scar after traumatic perforations not only induces corneal opacity, but also increases corneal HOAs, which indicates a direct effect on visual acuity. Abstract : Supplemental Digital Content is Available in the Text.