Successful Treatment of Granulomatous Mastitis Associated With Corynebacterium kroppenstedtii With Prolonged Antimicrobial Therapy. Issue 2 (March 2019)

• Record Type: Journal Article
• Authors: Waldron, Ruth; Mohamed, Aia; Boyle, Breida; Al-Azawi, Dhafir; O'Connell, Brian
• Is Part Of: Infectious diseases in clinical practice. Volume 27:Issue 2(2019:Mar.)
• Publication Date: 2019-03
• Subjects: Corynebacterium kroppenstedtii -- granulomatous mastitis -- lipophilic; Communicable diseases -- Periodicals; Communicable Diseases -- Periodicals; Communicable diseases; Periodicals; Periodicals; Electronic journals; 616.9
• DOI: 10.1097/IPC.0000000000000699
• Languages: English
• ISSNs: 1056-9103

Abstract

Abstract : Abstract: Granulomatous mastitis is a rare breast disease that classically occurs in parous women of reproductive age. In recent years, an association has been reported between this condition and Corynebacterium species, which are gram-positive bacilli that are endogenous to the skin. We describe a case of granulomatous mastitis associated with Corynebacterium kroppenstedtii, a lipophilic organism with an affinity for the lipid-rich mammary glands. We highlight the need to consider this pathogen to guide investigation and describe the diagnostic challenges related to isolation and identification of the organism. In addition, we report on successful treatment of the patient with a prolonged course of a combination of clarithromycin and rifampin. Abstract : This article describes a case of granulomatous mastitis associated with Corynebacterium kroppenstedtii . It is an organism that is challenging to diagnose and treat. The article highlights the need to consider this pathogen and describes the conditions required for microbiological diagnosis. In addition, the authors describe the successful treatment of this infection with prolonged combination therapy.