Joint factorial structure of psychopathology and personality. Issue 13 (5th November 2018)

• Record Type: Journal Article
• Authors: Rosenström, Tom; Gjerde, Line C.; Krueger, Robert F.; Aggen, Steven H.; Czajkowski, Nikolai Olavi; Gillespie, Nathan A.; Kendler, Kenneth S.; Reichborn-Kjennerud, Ted; Torvik, Fartein Ask; Ystrom, Eivind
• Is Part Of: Psychological medicine. Volume 49:Issue 13(2019)
• Page Start: 2158
• Page End: 2167
• Publication Date: 2018-11-05
• Subjects: Behavior genetics, -- Big Five personality traits, -- DSM-5 Section III personality traits, -- factor analysis, -- p factor, -- psychiatric comorbidity; Psychiatry -- Periodicals; Medicine and psychology -- Periodicals; Clinical psychology -- Periodicals; 616.89
• DOI: 10.1017/S0033291718002982
• Languages: English
• ISSNs: 0033-2917

Abstract

Abstract: Background: Normative and pathological personality traits have rarely been integrated into a joint large-scale structural analysis with psychiatric disorders, although a recent study suggested they entail a common individual differences continuum. Methods: We explored the joint factor structure of 11 psychiatric disorders, five personality-disorder trait domains (DSM-5 Section III), and five normative personality trait domains (the 'Big Five') in a population-based sample of 2796 Norwegian twins, aged 19‒46. Results: Three factors could be interpreted: (i) a general risk factor for all psychopathology, (ii) a risk factor specific to internalizing disorders and traits, and (iii) a risk factor specific to externalizing disorders and traits. Heritability estimates for the three risk factor scores were 48% (95% CI 41‒54%), 35% (CI 28‒42%), and 37% (CI 31‒44%), respectively. All 11 disorders had uniform loadings on the general factor (congruence coefficient of 0.991 with uniformity). Ignoring sign and excluding the openness trait, this uniformity of factor loadings held for all the personality trait domains and all disorders (congruence 0.983). Conclusions: Based on our findings, future research should investigate joint etiologic and transdiagnostic models for normative and pathological personality and other psychopathology.