AgSCF3-mediated trifluoromethylthiolation of α, α-diaryl allylic alcohols via radical neophyl rearrangement. Issue 3 (5th January 2017)

• Record Type: Journal Article
• Authors: Liu, Kai; Jin, Qiao; Chen, Shuang; Liu, Pei Nian
• Is Part Of: RSC advances. Volume 7:Issue 3(2017)
• Page Start: 1546
• Page End: 1552
• Publication Date: 2017-01-05
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra25378d
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A novel example of AgSCF3 -mediated oxidative radical trifluoromethylthiolation of α, α-diaryl allylic alcohols is presented, producing various α-aryl-β-trifluoromethylthiolated carbonyl ketones via radical neophyl rearrangement under mild conditions. Abstract : A novel example of AgSCF3 -mediated oxidative radical trifluoromethylthiolation of α, α-diaryl allylic alcohols is presented, producing various α-aryl-β-trifluoromethylthiolated carbonyl ketones via radical neophyl rearrangement under mild conditions. This protocol involves formation of C(Ar)–C(sp 3 ) and C(sp 3 )–S bonds in one step and tolerates a wide range of symmetrical and nonsymmetrical α, α-diaryl allylic alcohols.