Compounds from the root of Pueraria peduncularis (Grah. ex Benth.) Benth. and their antimicrobial effects. Issue 10 (27th March 2019)

• Record Type: Journal Article
• Authors: Chen, Huabao; Zhao, Xiaomin; Lv, Tianxing; Qiu, Xiaoyan; Luo, Liya; Zhang, Min; Yang, Hui; Chang, Xiaoli; Li, Peili; Wu, ChuanLei; Xie, Deshan; Qian, Yong; Yang, Chunping
• Is Part Of: Pest management science. Volume 75:Issue 10(2019)
• Page Start: 2765
• Page End: 2769
• Publication Date: 2019-03-27
• Subjects: Pueraria peduncularis -- antimicrobial activity -- medicarpin -- puercarpan A -- Rhizoctonia solani; Pests -- Control -- Periodicals; Pesticides -- Periodicals; 632.9
• DOI: 10.1002/ps.5387
• Languages: English
• ISSNs: 1526-498X

Abstract

ABSTRACT: BACKGROUND: Pueraria peduncularis belongs to the genus Pueraria DC, and has a wide range of medical and agricultural activities. Previous studies have shown that P. peduncularis extracts have broad bioactivities against phytopathogens. In this paper, we systematically studied the fungicidal activity of root methanol extracts and further isolated the active compounds. RESULTS: The root methanol extract inhibited the mycelial growth of the five tested phytopathogens to different degrees. Among these phytopathogens, the inhibitory effect was greatest against R. solani, with an EC50 value of 324.72 mg L −1 . Eight compounds were subsequently isolated and identified from P. peduncularis . Among them, puercarpan A and medicarpin showed strong fungicidal activity, with MIC values against Rhizoctonia solani of 1.6 and 6.25 mg L −1, respectively. Puercarpan A is a new compound, and its structure was established as (6aR, 6bS, 11aR)‐6b‐hydroxy‐3‐methoxypterocarpan‐10‐ene‐7‐one. CONCLUSION: The P. peduncularis extracts exhibit high antimicrobial activity against R. solani and have great potential value of P. peduncularis as a fungicide. © 2019 Society of Chemical Industry Abstract : Pueraria peduncularis belongs to the genus Pueraria DC, we systematically studied the fungicidal activity of root methanol extracts and further isolated the active compounds.