T-cell lymphoblastic lymphoma involving the ocular adnexa: report of two cases and review of the current literature. (3rd September 2019)

• Record Type: Journal Article
• Authors: Sun, Lucy; Friedman, Alan H.; Rodgers, Rand; Schear, Matthew; Greaves, Giovanni; Freidl, Kathryn B.
• Is Part Of: Orbit. Volume 38:Number 5(2019)
• Page Start: 412
• Page End: 418
• Publication Date: 2019-09-03
• Subjects: T-cell -- precursor -- lymphoblastic lymphoma -- ocular adnexa -- orbit; Eye-sockets -- Surgery -- Periodicals; Eye-sockets -- Diseases -- Periodicals; Orbit -- surgery -- Periodicals; Orbital Diseases -- Periodicals; 617.7
• DOI: 10.1080/01676830.2018.1540013
• Languages: English
• ISSNs: 0167-6830

Abstract

ABSTRACT: The majority of ocular adnexal lymphomas are B-cell in origin. We report two cases of T-cell lymphoblastic lymphoma (T-LBL) involving the ocular adnexa. One patient presented with a painless pink conjunctival lesion and inferior orbital fullness. The second patient presented with a painless orbital mass. The diagnoses were confirmed by histopathology and immunohistochemistry. Both patients had extensive multifocal lesions during staging. Prompt intensified chemotherapy regimens were initiated. T-LBL is an aggressive disease with poor prognosis. This report emphasizes the importance of timely diagnosis by the ophthalmologist with co-management and treatment with an oncologist.