Bioactive phenolic acid-substituted glycoses and glycosides from rhizomes of Cibotium barometz. Issue 10 (3rd October 2019)

• Record Type: Journal Article
• Authors: Li, Lan; Xie, Mei-Ping; Sun, Hua; Lu, An-Qi; Zhang, Bo; Zhang, Dan; Wang, Su-Juan
• Is Part Of: Journal of Asian natural products research. Volume 21:Issue 10(2019)
• Page Start: 947
• Page End: 953
• Publication Date: 2019-10-03
• Subjects: Cibotium barometz -- phenolic acid -- allose -- hepatoprotection; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2018.1563076
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: Two rarely phenolic acid-substituted alloses (1, 2 ) and one new glucoside (3 ), as well as nine known compounds (4–12 ) were isolated from rhizomes of Cibotium barometz (L.) J. Sm. Structures of1–3 were established by extensively spectroscopic analyses (NMR, MS, etc.) and acid hydrolysis. All compounds were evaluated for the hepatoprotective activities against APAP-induced HepG2 cell damage. Compounds1, 4 –7, 10 exhibited significant hepatoprotective activities, even more strongly than positive control, bicycol. In addition, compounds1 and9 could reduce PC12 cell death induced by serum deprivation. Abstract :