Enzyme-catalysed enantioselective oxidation of alcohols by air exploiting fast electrochemical nicotinamide cycling in electrode nanopores. Issue 18 (30th August 2019)

• Record Type: Journal Article
• Authors: Wan, Lei; Heath, Rachel S.; Siritanaratkul, Bhavin; Megarity, Clare F.; Sills, Adam J.; Thompson, Matthew P.; Turner, Nicholas J.; Armstrong, Fraser A.
• Is Part Of: Green chemistry. Volume 21:Issue 18(2019)
• Page Start: 4958
• Page End: 4963
• Publication Date: 2019-08-30
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/c9gc01534e
• Languages: English
• ISSNs: 1463-9262

Abstract

Abstract : Enantioselective conversion of alcohols to ketones using air as the oxidant is achieved with high rates and efficiency using an indium tin oxide electrode in which an alcohol dehydrogenase and a NADPH recycling enzyme are confined within nanopores. Abstract : Enantioselective conversion of alcohols to ketones using air as the oxidant is achieved with high rates and efficiency using an indium tin oxide (ITO) electrode in which an alcohol dehydrogenase and a photosynthetic NADPH recycling enzyme are confined within nanopores. The massive catalytic enhancement arising from nanoconfinement is exploited in an air-driven electrochemical cell, which requires no complicating control features yet allows continuous monitoring of the reaction via the current that flows between anode (ITO: organic chemistry) and cathode (Pt: O2 from air).