MiRNAs induced by white spot syndrome virus involve in immunity pathways in shrimp Litopenaeus vannamei. Issue 93 (October 2019)

• Record Type: Journal Article
• Authors: Wu, Wenlin; Dai, Congjie; Duan, Xunwei; Wang, Cuifang; Lin, Xiaosi; Ke, Jiaying; Wang, Yixuan; Zhang, Xiaobo; Liu, Haipeng
• Is Part Of: Fish & shellfish immunology. Issue 93(2019)
• Page Start: 743
• Page End: 751
• Publication Date: 2019-10
• Subjects: miRNAs -- WSSV -- Litopenaeus vannamei -- Immunity; Fishes -- Immunology -- Periodicals; Shellfish -- Immunology -- Periodicals; Poissons -- Immunologie -- Périodiques; Crustacés -- Immunologie -- Périodiques; 571.9617
• DOI: 10.1016/j.fsi.2019.08.009
• Languages: English
• ISSNs: 1050-4648

Abstract

Abstract: White shrimp Litopenaeus vannamei are widely cultured in the world and white spot syndrome virus (WSSV) led to huge economic losses in the shrimp industry every year. In the present study, miRNAs involved in the response of shrimp L. vannamei to WSSV infection were obtained through the Illumina HiSeq 2500 high-throughput next-generation sequencing technique. A total number of 7 known miRNAs and 54 putative novel miRNAs were obtained. Among them, 14 DEMs were identified in the shrimp infected with WSSV. The putative target genes of these DEMs were related to host immune response or signaling pathways, indicating the importance of miRNAs in shrimp against WSSV infection. The results will provide information for further research on shrimp response to virus infection and contribute to the development of new strategies for effective protection against WSSV infections. Highlights: The miRNAs of shrimp L. vannamei treated with WSSV was examined by RNA-seq. 7 known miRNAs and 54 putative novel miRNAs were obtained. 14 DEMs were identified in the shrimp infected with WSSV. The putative target genes of these DEMs were related to immunity signaling pathways.