Manipulation of the ATP pool as a tool for metabolic engineering. (27th November 2015)
- Record Type:
- Journal Article
- Title:
- Manipulation of the ATP pool as a tool for metabolic engineering. (27th November 2015)
- Main Title:
- Manipulation of the ATP pool as a tool for metabolic engineering
- Authors:
- Hädicke, Oliver
Klamt, Steffen - Abstract:
- Abstract : Cofactor engineering has been long identified as a valuable tool for metabolic engineering. Besides interventions targeting the pools of redox cofactors, many studies addressed the adenosine pools of microorganisms. In this mini-review, we discuss interventions that manipulate the availability of ATP with a special focus on ATP wasting strategies. We discuss the importance to fine-tune the ATP yield along a production pathway to balance process performance parameters like product yield and volumetric productivity.
- Is Part Of:
- Biochemical Society transactions. Volume 43:Number 6(2015)
- Journal:
- Biochemical Society transactions
- Issue:
- Volume 43:Number 6(2015)
- Issue Display:
- Volume 43, Issue 6 (2015)
- Year:
- 2015
- Volume:
- 43
- Issue:
- 6
- Issue Sort Value:
- 2015-0043-0006-0000
- Page Start:
- 1140
- Page End:
- 1145
- Publication Date:
- 2015-11-27
- Subjects:
- adenosine 5′-triphosphate (ATP) futile cycling -- metabolic engineering -- product yield -- volumetric productivity
Biochemistry -- Congresses
572 - Journal URLs:
- https://portlandpress.com/biochemsoctrans ↗
- DOI:
- 10.1042/BST20150141 ↗
- Languages:
- English
- ISSNs:
- 0300-5127
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD Digital store
- Ingest File:
- 11654.xml