Fabrication of graphene/azobenzene-perylene diimide derivative modified electrochemical sensors for the dopamine detection based on full factorial experimental design. (December 2019)

• Record Type: Journal Article
• Authors: Ören Varol, Tuğba; Perk, Benay; Avci, Okan; Akpolat, Oğuz; Hakli, Özgül; Xue, Chenming; Li, Quan; Anik, Ülkü
• Is Part Of: Measurement. Volume 147(2019)
• Publication Date: 2019-12
• Subjects: Dopamine -- Graphene -- Perylene diimide -- Full factorial design -- Experimental design; Weights and measures -- Periodicals; Measurement -- Periodicals; Measurement; Weights and measures; Periodicals; 530.8
• DOI: 10.1016/j.measurement.2019.106867
• Languages: English
• ISSNs: 0263-2241

Abstract

Highlights: Azobenzene derived perylene diimide and graphene were used for sensor fabrication. The developed electrochemical sensor provided 2.2-fold increase in dopamine signal. Full factorial design was utilized to optimize the experimental parameters. Dopamine hydrochloride injection samples were analyzed with satisfactory results. Abstract: In this study, carbon paste electrode (CPE) was modified with graphene and a novel azobenzene-perylene diimide derivative (P4 SAc) and utilized for the dopamine detection. Electrochemical performances of modified electrochemical platforms were examined and graphene/P4 SAc/CPE exhibited the highest increment in dopamine oxidation signal. Experimental parameters were optimized by using full factorial design and analytical characteristics were examined. As a result, a linear range was obtained in the concentration range of 5–100 µM with a detection limit of 0.26 µM ( n = 3). The developed sensor was also applied for the dopamine detection in injection samples and very promising results were obtained.