Assessment of Dechlorane Plus and related compounds in foodstuffs and estimates of daily intake from Lebanese population. (November 2019)

• Record Type: Journal Article
• Authors: Abdel Malak, Inas; Cariou, Ronan; Guiffard, Ingrid; Vénisseau, Anaïs; Dervilly-Pinel, Gaud; Jaber, Farouk; Le Bizec, Bruno
• Is Part Of: Chemosphere. Volume 235(2019)
• Page Start: 492
• Page End: 497
• Publication Date: 2019-11
• Subjects: Chlorinated flame retardants -- Environmental contaminants -- Ultra-trace measurement -- Food analysis -- Human intake -- Chemical risk; Pollution -- Periodicals; Pollution -- Physiological effect -- Periodicals; Environmental sciences -- Periodicals; Atmospheric chemistry -- Periodicals; 551.511
• DOI: 10.1016/j.chemosphere.2019.06.148
• Languages: English
• ISSNs: 0045-6535

Abstract

Abstract: Dechlorane Related Compounds (DRCs), including Dechlorane Plus ( syn/anti -DP or syn/anti -DDC-CO) and related compounds (Dec-601 or DDC-ID, Dec-602 or DDC-DBF, Dec-603 or DDC-Ant and Chlordene Plus or DDC-PDD), are a group of polychlorinated flame retardants of concern since they were first reported in various environmental and biota matrices about one decade ago. In this work, we investigated the dietary intake of the Lebanese population to these lipophilic environmental contaminants upon the evaluation of selected foodstuff contamination. Collected food samples (n = 58) were selected to be representative of the lipid fraction of the whole diet of the Beiruti population. The samples were analysed using pressurized liquid extraction, silica multilayer column followed by gel permeation chromatography for purification and GC-EI-HRMS for separation and detection. Detection frequency of at least one compound among Dechlorane Plus ( syn -DP and anti -DP), Dechlorane 602, 603 and Chlordene Plus) was 91%. The mean concentrations of ∑6 DRCs, by food group, ranged from 4.7 to 29.5 pg g −1 wet weight in lowerbound (LB) and from 6.7 to 76.9 pg g −1 wet weight in upperbound (UB). Based on food habits, the dietary intake of Beiruti adults was estimated to be between 3.71 (LB) and 5.61 (UB) ng day −1 . Dechlorane Plus and Dechlorane 602 were the dominant compounds, contributing to 70 and 24% of the total intake (LB value), respectively. This study reports for the first time the occurrence of Dechloranes in Lebanese foods and proposes corresponding deterministic dietary exposure scenario. Graphical abstract: Image 1 Highlights: Dechlorane Related Compounds (DRCs) quantified for the first time in Lebanese food. Concentrations of DRCs measured at the pg g −1 ww level. Daily intake estimated between 3.71 and 5.61 ng per person daily. DP and Dec-602, meat and poultry, as major contributors to DRCs dietary exposure.