An Organ-On-A-Chip Engineered Platform to Study the Microbiota–Gut–Brain Axis in Neurodegeneration. Issue 9 (September 2019)

• Record Type: Journal Article
• Authors: Raimondi, Manuela Teresa; Albani, Diego; Giordano, Carmen
• Is Part Of: Trends in molecular medicine. Volume 25:Issue 9(2019)
• Page Start: 737
• Page End: 740
• Publication Date: 2019-09
• Subjects: microbiota–gut–brain axis -- organ-on-a-chip -- neurodegeneration -- personalized medicine; Molecular biology -- Periodicals; Pathology, Molecular -- Periodicals; Physiology, Pathological -- Periodicals; 572.8
• DOI: 10.1016/j.molmed.2019.07.006
• Languages: English
• ISSNs: 1471-4914

Abstract

Abstract : After decades of research, the etiology of neurodegenerative disorders such as Alzheimer's or Parkinson's disease is still mostly unknown. Recent findings indicate that the microorganisms in the human gut might be involved in neurodegenerative pathways. Here, we discuss an innovative groundbreaking bioengineering approach that could make a difference in this intriguing scenario.