Rhodium catalyzed template-assisted distal para-C–H olefination. Issue 31 (27th June 2019)

• Record Type: Journal Article
• Authors: Dutta, Uttam; Maiti, Sudip; Pimparkar, Sandeep; Maiti, Siddhartha; Gahan, Lawrence R.; Krenske, Elizabeth H.; Lupton, David W.; Maiti, Debabrata
• Is Part Of: Chemical science. Volume 10:Issue 31(2019)
• Page Start: 7426
• Page End: 7432
• Publication Date: 2019-06-27
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c9sc01824g
• Languages: English
• ISSNs: 2041-6520

Abstract

Abstract : We report first example of template assisted rhodium catalyzed para -C–H alkenylation. Abstract : Rhodium catalysis has been extensively used for ortho -C–H functionalization reactions, and successfully extended to meta -C–H functionalization. Its application to para -C–H activation remains an unmet challenge. Herein we disclose the first example of such a reaction, with the Rh-catalyzed para -C–H olefination of arenes. The use of a Si-linked cyanobiphenyl unit as a traceless directing group leads to highly para -selective arene–olefin couplings.