Successful treatment of metachronous contralateral intratubular germ cell neoplasia with partial orchiectomy and low‐dose radiation in a patient previously treated for testicular carcinoma. Issue 10 (9th June 2019)

• Record Type: Journal Article
• Authors: Schneller, Netta; Grimes, Amanda; Muscal, Jodi; Quintanilla, Norma; Mittal, Angela; Paulino, Arnold; Foster, Jennifer
• Is Part Of: Pediatric blood & cancer. Volume 66:Issue 10(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-06-09
• Subjects: germ cell tumors -- pediatric oncology -- radiation oncology -- radiation therapy -- solid tumors; Tumors in children -- Periodicals; Blood -- Diseases -- Periodicals; Cancer in children -- Periodicals; 618.92
• DOI: 10.1002/pbc.27872
• Languages: English
• ISSNs: 1545-5009

Abstract

Abstract: Intratubular germ cell neoplasia (ITGCN) of the testis is a precursor to testicular germ cell tumor (TGCT), which can lead to the development of invasive cancer. In patients with a history of previously treated unilateral TGCT, treatment for ITGCN of the contralateral testis needs to be balanced with the risks of subsequent infertility. Here, we present a 17‐ year‐ old patient with ITGCN diagnosed after treatment of contralateral nonseminomatous TGCT who was successfully treated with a partial orchiectomy followed by low‐dose radiation with preservation of his testosterone production.