Benzisothiazol‐3‐ones through a Metal‐Free Intramolecular N–S Bond Formation. Issue 40 (18th October 2018)

• Record Type: Journal Article
• Authors: Yang, Ke; Zhang, Hao; Niu, Ben; Tang, Tiandi; Ge, Haibo
• Is Part Of: European journal of organic chemistry. Issue 40(2018)
• Page Start: 5520
• Page End: 5523
• Publication Date: 2018-10-18
• Subjects: Cleavage reactions -- Cyclization -- Synthetic methods -- Selectfluor -- Sulfur heterocycles; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201801090
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : The highly efficient synthesis of benzoisothiazol‐3‐ones from thiobenzamides has been described with good functional group compatibility and excellent yields. This work represents the first example of selectfluor‐promoted N–S bond formation processes. This method provides a facile approach to access various important bioactive benzoisothiazol‐3‐ones. Abstract : An efficient selectfluor‐promoted synthesis of benzoisothiazol‐3‐ones through a sequential N–S bond formation and C–S bond cleavage process was developed.