Advances in tissue engineering of nanocellulose-based scaffolds: A review. (15th November 2019)

• Record Type: Journal Article
• Authors: Luo, Huize; Cha, Ruitao; Li, Juanjuan; Hao, Wenshuai; Zhang, Yan; Zhou, Fengshan
• Is Part Of: Carbohydrate polymers. Volume 224(2019)
• Publication Date: 2019-11-15
• Subjects: AceNFC acetylated NFC -- A-NCC aldehyde-functionalized NCC -- BANFC brown algae NFC -- BANFC/QCR BANFC/quaternized chitin/organic rectorite -- BC bacterial cellulose -- BCW bacterial cellulose whiskers -- CAP cellulose acetate propionate -- CNT carbon nanotubes -- CP calcium peroxide -- DMSO dimethyl sulfoxide -- DO degree of oxidation -- ECCNN electrospun cellulose/NCC nanocomposite nanofibers -- ECM extracellular matrix -- GelMA gelatin methacrylate -- HG hyaluronan-gelatin -- MANFC maleic anhydride modified NFC -- MCC microcrystalline cellulose -- MEO2MA 2-(2′-Methoxyethoxy)ethyl methacrylate -- MFC microfibrillated cellulose -- NC nanocellulose -- NCC nanocrystalline cellulose -- NFC nanofibrillated cellulose -- NIPAM N-isopropylacrylamide -- OEGMA oligo(ethylene glycol)methacrylate -- PBS poly(butylene succinate) -- PLA poly(lactic acid) -- PLGA polylactide-polyglycolide -- POEGMA poly(oligoethylene glycol methacrylate) -- PU polyurethane -- PVA polyvinyl alcohol -- TE tissue engineering -- TEMPO 2, 2, 6, 6-tetramethylpiperidine-1-oxyl; Nanocrystalline cellulose -- Nanofibrillated cellulose -- Tissue engineering -- Scaffold; Polysaccharides -- Periodicals; Polysaccharides -- Periodicals; Polysaccharides -- Périodiques; Electronic journals; 547.78
• DOI: 10.1016/j.carbpol.2019.115144
• Languages: English
• ISSNs: 0144-8617

Abstract

Highlights: We discussed the tissue engineering applications of nanocellulose-based scaffolds. We summarized methods to prepare scaffolds such as electrospinning and 3D printing. We highlighted the repairing and replacement of heart, liver and ophthalmology. We outlined the challenges and potentials of nanocellulose-based scaffolds. Abstract: Scaffolds based on nanocellulose (NC) have crucial applications in tissue engineering (TE) owing to the biocompatibility, water absorption, water retention, optical transparency, and chemo-mechanical properties. In this review, we summarize the scaffolds based on nanocellulose, including nanocrystalline cellulose and nanofibrillated cellulose. We compare four representative methods to prepare NC-based scaffolds, containing electrospinning, freeze-drying, 3D printing, and solvent casting. We outline the characteristics of scaffolds obtained by different methods. Our focus is on the applications of NC-based scaffolds to repair, improve or replace damaged tissues and organs, including skin, blood vessel, nerve, skeletal muscle, heart, liver, and ophthalmology. NC-based scaffolds are attractive materials for regeneration of different tissues and organs due to the remarkable features. Finally, we propose the challenges and potentials of NC-based TE scaffolds.