High‐frequency ultrasonography—New non‐invasive method in assessment of skin lymphomas. Issue 3 (31st January 2018)

• Record Type: Journal Article
• Authors: Polańska, A.; Dańczak‐Pazdrowska, A.; Olek‐Hrab, K.; Osmola‐Mańkowska, A.; Bowszyc‐Dmochowska, M.; Żaba, R.; Adamski, Z.
• Is Part Of: Skin research and technology. Volume 24:Issue 3(2018)
• Page Start: 517
• Page End: 521
• Publication Date: 2018-01-31
• Subjects: High‐frequency ultrasonography -- mycosis fungoides -- skin lymphoma -- skin USG -- SLEB; Skin -- Research -- Periodicals; Skin -- Diseases -- Periodicals; Skin -- Physiology -- Periodicals; 616.5
• DOI: 10.1111/srt.12450
• Languages: English
• ISSNs: 0909-752X

Abstract

Abstract: Background: Mycosis fingoides (MF) is the most common subtype of primary cutaneous T‐cell lymphomas. Current evaluation of disease extent and severity is based on mSWAT scoring system, which seems to be relatively subjective. The aim of this subject was to present the usefulness of 20 MHz in objective 5‐year long monitoring of response to therapy in MF patients. Materials and methods: The 5‐years long follow‐up based on 19 skin USG images of patients diagnosed as early stages of MF was studied. The assessed USG parameter was the mean diameter of subepidermal low echogenic band (SLEB). Results: In every MF patient during exacerbation within lesional skin we could observe SLEB, which thinning or complete disappearance was detected after finishing the therapy. Lack of complete absence of SLEB was related to the lack of complete remission assessed by mSWAT. Conclusion: We present for the first time the possibility of monitoring patients' clinical state on the base of non‐invasive USG imaging. We recommend additional use of 20 MHz USG to reduce intra‐observer variability and to assess residual disease. USG imaging can complement evaluation of skin lesions in MF and can support clinical judgement.