Proximal hypospadias treated with a transverse preputial island tube: long‐term functional, sexual, and cosmetic outcomes. (1st May 2018)

• Record Type: Journal Article
• Authors: Rynja, Sybren P.; de Jong, Tom P.V.M.; Bosch, J.L.H. Ruud; de Kort, Laetitia M.O.
• Is Part Of: BJU international. Volume 122:Number 3(2018)
• Page Start: 463
• Page End: 471
• Publication Date: 2018-05-01
• Subjects: Hypospadias -- Sexual development -- Postoperative complication -- Patient‐reported outcome -- Cosmetic technique; Genitourinary organs -- Diseases -- Periodicals; Genitourinary organs -- Surgery -- Periodicals; Urology -- Periodicals; 616.6
• DOI: 10.1111/bju.14234
• Languages: English
• ISSNs: 1464-4096

Abstract

Abstract : Objective: To study long‐term urinary and sexual function, and cosmetic outcomes in adult patients who underwent single‐stage transverse preputial island tube (TPIT) for proximal hypospadias repair in childhood. Long‐term data on outcomes of patients with proximal hypospadias with severe coexisting curvature and insufficient urethral plate are scarce, but are necessary to decide which repair technique is most beneficial. Patients, Subjects and Methods: Patients with proximal hypospadias operated with TPIT (TPIT Group) were compared to patients with distal hypospadias repair (Distal Group) and to a control group of male medical students (Control Group). Participants completed the International Prostate Symptom Score, the International Index of Erectile Function (IIEF‐15), additional non‐validated questions, and performed uroflowmetry. Cosmesis was assessed in the patients with hypospadias using the Pediatric Penile Perception Score (PPPS); stretched penile length was also measured. Results: Of the 121 eligible patients with hypospadias, 54 with either TPIT or distal hypospadias repairs participated. The TPIT Group comprised 12 patients (median age of 20.0 years) and the Distal Group comprised 42 patients (median age of 19.6 years). The complication rates were similar, at 8 of the 12 patients in the TPIT Group vs 26/42 (62%) in the Distal Group ( P = 0.76). Urinary outcomes were similar in the TPIT, Distal, and the Control (comprised of 148 medical students with a median age of 21.0 years) groups. The TPIT Group had a lower maximum urinary flow rate compared to the Control Group, at 24.1 vs 28.6 mL/s ( P < 0.05). IIEF‐15 scores were similar in the TPIT, Distal and Control groups, except for 'Orgasmic Function' (7.5 vs 10.0 vs 10.0, respectively; P < 0.01). Although the TPIT Group had a smaller penile length compared to the Distal Group (10.1 vs 12.9 cm, P < 0.01), PPPS outcomes were similar. Conclusion: In these TPIT patients, long‐term urinary, sexual and cosmetic outcomes were similar to those in patients with distal hypospadias repairs and controls.