Successful treatment of multidrug resistant Klebsiella pneumoniae using dual carbapenem regimen in immunocompromised patient. (2017)

• Record Type: Journal Article
• Authors: El Nekidy, Wasim S.; Mooty, Mohamad Y.; Attallah, Nizar; Cardona, Lyssette; Bonilla, Maria Fernanda; Ghazi, Islam M.
• Is Part Of: IDCases. Volume 9(2017)
• Page Start: 53
• Page End: 55
• Publication Date: 2017
• Subjects: Carbapenem resistant -- Klebsiella Pneumoniae -- Double carbapenem regimen -- Imunocompromised; Communicable diseases -- Periodicals; Communicable Diseases -- Case Reports; Communicable Diseases -- Periodicals; Communicable diseases; Periodicals; 616.9
• DOI: 10.1016/j.idcr.2017.06.005
• Languages: English
• ISSNs: 2214-2509

Abstract

Abstract: This report describes a longitudinal case of immunocompromised patient post kidney transplant who was admitted to our institution repeatedly for treatment of various infections caused by multi-drug resistant Klebsiella pneumoniae. The patient was successfully treated with a combination of ertapenem/meropenem on multiple occasions despite the elevated MICs. Our observations corroborate previous preclinical studies and case reports showing the efficacy of double carbapenem regimens against resistant Enterobacteriaceae.