Flaming Mitochondria: The Anti-inflammatory Drug Leflunomide Boosts Mitofusins. Issue 3 (15th March 2018)

• Record Type: Journal Article
• Authors: Pellattiero, Anna; Scorrano, Luca
• Is Part Of: Cell chemical biology. Volume 25:Issue 3(2018)
• Page Start: 231
• Page End: 233
• Publication Date: 2018-03-15
• Subjects: Biochemistry -- Periodicals; 572.05
• DOI: 10.1016/j.chembiol.2018.02.014
• Languages: English
• ISSNs: 2451-9456

Abstract

Abstract : Despite the significance of mitochondrial dynamics in many diseases, drugs that modulate it are lacking. In this issue of Cell Chemical Biology, Miret-Casals et al. (2018) use a phenotypic high-throughput screen to discover a pro-fusion role for the anti-inflammatory drug Leflunomide, paving the way to screen for mitochondrial pro-fusion drug candidates. Abstract : Despite the significance of mitochondrial dynamics in many diseases, drugs that modulate it are lacking. In this issue of Cell Chemical Biology, Miret-Casals et al. (2018) use a phenotypic high-throughput screen to discover a pro-fusion role for the anti-inflammatory drug Leflunomide, paving the way to screen for mitochondrial pro-fusion drug candidates.