Muscle endurance deficits in myositis patients despite normal manual muscle testing scores. Issue 1 (18th December 2018)

• Record Type: Journal Article
• Authors: Amici, David R.; Pinal‐Fernandez, Iago; Pagkatipunan, Ruben; Mears, Albert; de Lorenzo, Rebecca; Tiniakou, Eleni; Albayda, Jemima; Paik, Julie J.; Lloyd, Thomas E.; Christopher‐STINE, Lisa; Mammen, Andrew L.; Chung, Tae
• Is Part Of: Muscle & nerve. Volume 59:Issue 1(2019)
• Page Start: 70
• Page End: 75
• Publication Date: 2018-12-18
• Subjects: functional index -- muscle strength -- myositis -- neuromuscular diseases -- physical endurance; Neuromuscular diseases -- Periodicals; Muscles -- Periodicals; Nerves -- Periodicals; 616.74
• DOI: 10.1002/mus.26307
• Languages: English
• ISSNs: 0148-639X

Abstract

ABSTRACT: Introduction : It is unclear whether quantitating muscle endurance adds nonredundant information useful for the care of patients with muscular disease. Methods : Records were retrospectively reviewed for all Johns Hopkins Myositis Center patients with a muscle endurance assessment ( n = 128, 226 patient‐visits). Muscle endurance and strength were quantitated with the Myositis Functional Index‐2 (FI2) and manual muscle testing (MMT), respectively. Results : Composite FI2 muscle endurance scores were comparable in inclusion body myositis ( n = 58), dermatomyositis ( n = 31), and polymyositis ( n = 39). Overall, muscle endurance correlated with and evolved similarly to strength, inversely to serum creatine kinase. However, in patients with normal or near‐normal strength (mean MMT > 9.75/10), muscle endurance was typically abnormal and highly variable (mean FI2, 5.6/10; interquartile range, 3.3‐7.8/10). Discussion : Muscle endurance testing may identify muscle impairment inadequately described by MMT, particularly in patients with high MMT scores. Muscle Nerve 59 :70–75, 2019