A novel integrative phylogenetic analysis system. (6th August 2010)

• Record Type: Journal Article
• Authors: Wang, Penghao; Zhou, Bing Bing; Wang, Chen; Zomaya, Albert Y.
• Is Part Of: International journal of computational biology and drug design. Volume 3:Number 1(2010)
• Page Start: 1
• Page End: 14
• Publication Date: 2010-08-06
• Subjects: phylogeny reconstruction -- integration -- interactive computing -- multidisciplinary analysis -- quartet-based -- phylogenetic analysis -- computational methods -- computational biology; Computational biology -- Periodicals; Drugs -- Design -- Periodicals; 570.285
• Languages: English
• ISSNs: 1756-0756

Abstract

Existing phylogenetic methods cannot realistically model the evolutionary process. It has become a serious issue for real-life applications which demand accurate phylogenetic results. It is desirable to have an integrative approach which can effectively incorporate multi-disciplinary analyses and synthesise results from various sources. A novel integrative and interactive computing system has been developed to address such an issue. We introduce the concept of super-quartet and explain how it is adopted for effective integration of other computational methods to the algorithm during computation – a key issue of the development of integrative and interactive computing system.