Assessing truncal obesity in predicting cardiometabolic risk in children: clinical measures versus dual‐energy X‐ray absorptiometry. (22nd December 2017)

• Record Type: Journal Article
• Authors: Palmieri, Vincent J.; Henshaw, Melissa H.; Carter, Janet; Chowdhury, Shahryar M.
• Is Part Of: Acta pædiatrica. Volume 107:Number 6(2018)
• Page Start: 1065
• Page End: 1069
• Publication Date: 2017-12-22
• Subjects: Dyslipidemia -- Insulin resistance -- Obesity -- Truncal fat; Pediatrics -- Periodicals; Pediatrics; 618.92
• DOI: 10.1111/apa.14175
• Languages: English
• ISSNs: 0803-5253

Abstract

Abstract: Aim: The objectives of this study were to 1) compare the accuracy of waist:hip ratio (WHR) and waist:height ratio (WHtR) by determining their association with reference‐standard measures derived from dual‐energy X‐ray absorptiometry (DXA) and 2) assess the relationship of DXA, WHR and WHtR to measures of dyslipidemia, insulin resistance and inflammation in children. Methods: Subjects aged four to 21 were prospectively recruited. Truncal obesity by DXA was defined as the trunk fat:height ratio and trunk fat:nontrunk fat ratio. Three hundred and eight subjects were studied, and 246 (80%) were obese. Results: There was a strong correlation between WHtR and trunk fat:height (r = 0.84, p < 0.01). DXA measures of truncal obesity had stronger correlations with measures of cardiometabolic risk than WHR and WHtR. Upon multivariable regression, only WHtR had independent associations with cholesterol/HDL, HOMA‐IR and high‐sensitivity c‐reactive protein. Conclusion: WHtR is an accurate measure of truncal obesity. WHtR showed stronger associations with measures of insulin resistance and truncal obesity than WHR.