Can response to dietary restriction predict weight loss after Roux‐en‐Y gastroplasty?. Issue 4 (8th February 2016)

• Record Type: Journal Article
• Authors: Azar, Mirna; Nikpay, Majid; Harper, Mary‐Ellen; McPherson, Ruth; Dent, Robert
• Is Part Of: Obesity. Volume 24:Issue 4(2016)
• Page Start: 805
• Page End: 811
• Publication Date: 2016-02-08
• Subjects: Obesity -- Periodicals; 616.398005
• DOI: 10.1002/oby.21395
• Languages: English
• ISSNs: 1930-7381

Abstract

Abstract : Objective: To determine whether weight loss (WL) with 6 weeks of a low‐calorie liquid diet as part of a behavioral program (LCDBP) predicts subsequent weight change in response to a laparoscopic Roux‐en‐Y gastric bypass (RYGB). Methods: Of 4698 LCDBP patients, 403 went on to RYGB and 222 were evaluable. We determined correlations between percent WL (% WL) in 6 weeks of LCDBP with % WL at 4, 12, 24, 36, and 52 weeks after RYGB. Results: There was a positive correlation between the slope of WL in the first 6 weeks of LCDBP and over 4 and 12 weeks after RYGB: r = 0.15 (CI = 0.003‐0.285, P = 0.045) and r = 0.22 (CI = 0.08‐0.35, P = 0.0017), respectively. The association was also apparent at 24 weeks in females but not in males. There was a statistically significant correlation between % WL at 26 weeks of LCDBP and 52 weeks postsurgery ( r = 0.20, CI = 0.05‐0.34, P = 0.01). Finally, % WL at 6 weeks also predicted % WL at 26 weeks of dietary intervention ( r = 0.52, CI = 0.40‐0.62, P = 2.40 × 10 −14 ). Conclusions: WL in response to 6 weeks of LCDBP is predictive of weight for at least 12 weeks following RYGB.