Pityriasis Rubra Pilaris With Extensive Follicular Acantholysis Resembling Pemphigus Vulgaris: A Case Report. (January 2019)

• Record Type: Journal Article
• Authors: Lilo, Mohammed T.; Yan, Shaofeng; Chapman, Michael Shane; Linos, Konstantinos
• Is Part Of: American journal of dermatopathology. Volume 41:Number 1(2019)
• Publication Date: 2019-01
• Subjects: PRP -- acantholysis -- pemphigus vulgaris -- papulosquamous; Skin -- Diseases -- Periodicals; Histology, Pathological -- Periodicals; 616.50705
• DOI: 10.1097/DAD.0000000000001222
• Languages: English
• ISSNs: 0193-1091

Abstract

Abstract : Abstract: Pityriasis rubra pilaris (PRP) is a rare, chronic, heterogeneous, papulosquamous inflammatory dermatosis of unknown etiology. Although erythematous scaly patches characterize the classic presentation of PRP, a broad range of clinical presentations has been reported. Histologically, PRP is characterized by psoriasiform acanthosis with alternating orthokeratosis and parakeratosis and rarely small acantholytic foci. In this article, we report a patient who presented with diffuse erythroderma and extensive acantholysis mimicking pemphigus vulgaris histologically.