Improved Patient-Independent System for Detection of Electrical Onset of Seizures. Issue 1 (January 2019)

• Record Type: Journal Article
• Authors: Sridevi, Veerasingam; Ramasubba Reddy, Machireddy; Srinivasan, Kannan; Radhakrishnan, Kurupath; Rathore, Chaturbhuj; Nayak, Dinesh S.
• Is Part Of: Journal of clinical neurophysiology. Volume 36:Issue 1(2019)
• Publication Date: 2019-01
• Subjects: Epilepsy -- EEG -- Signal energy -- Spectral energy -- Spectral entropy -- Classifier; Electroencephalography -- Periodicals; Neurophysiology -- Periodicals; Electroencephalography -- Periodicals; Electroencephalography; Periodicals; 612.805
• DOI: 10.1097/WNP.0000000000000533
• Languages: English
• ISSNs: 0736-0258

Abstract

Abstract : Purpose: To design a non–patient-specific system to detect the electrical onset of seizures in patients with temporal lobe epilepsy. Methods: We used EEG data from 29 seizures of 18 temporal lobe epilepsy patients who underwent multiday video-scalp EEG monitoring as part of their presurgical evaluations. We segmented each data set into preictal and ictal phases, and identified spectral entropy, spectral energy, and signal energy as useful features for discriminating normal and seizure conditions. The performance of five different classifiers was analyzed using these features to design an automated detection system. Results: Among the five classifiers, decision tree, k-nearest neighbor, and support vector machine performed with sensitivity (specificity) of 79% (81%), 75% (85%), and 80% (86%), respectively. The other two, linear discriminant algorithm and Naive Bayes classifiers, performed with sensitivity (specificity) of 54% (94%), 47% (96%), respectively. Conclusions: The support vector machine–based seizure detection system showed better detection capability in terms of sensitivity and specificity measures as compared to linear discriminant algorithm, Naive Bayes, decision tree, and k-nearest neighbor classifiers. Conclusions: Our study shows that a generalized system to detect the electrical onset of seizures in temporal lobe epilepsy using scalp-recorded EEG is possible. If confirmed on a larger data set, our findings may have significant implications for the management of seizures, especially in patients with drug-resistant epilepsy.