Advantages of Integrating Pressure-Regulating Devices Into Mechanical Circulatory Support Pumps. Issue 1 (January 2019)

• Record Type: Journal Article
• Authors: Horvath, David J.; Karimov, Jamshid H.; Byram, Nicole A.; Kuban, Barry D.; Sunagawa, Gengo; Moazami, Nader; Fukamachi, Kiyotaka
• Is Part Of: ASAIO journal. Volume 65:Issue 1(2019)
• Publication Date: 2019-01
• Subjects: continuous-flow total artificial heart -- ventricular assist device -- automatic control -- sensorless -- passive regulation; Artificial organs -- Periodicals; 617
• DOI: 10.1097/MAT.0000000000000772
• Languages: English
• ISSNs: 1058-2916

Abstract

Abstract : Control of mechanical circulatory support pump output typically requires that pressure-regulating functions be accomplished by active control of the speed or geometry of the device, with feedback from pressure or flow sensors. This article presents a different design approach, with a pressure-regulating device as the core design feature, allowing the essential control function of regulating pressure to be directly programmed into the hydromechanical design. We show the step-by-step transformation of a pressure-regulating device into a continuous-flow total artificial heart that passively balances left and right circulations without the need for pressure and flow sensors. In addition, we discuss a ventricular assist device that prevents backflow in the event of power interruption and also dynamically interacts with residual ventricle function to preserve pulsatility.