Synthesis of β‐Trifluoromethylated Alkyl Azides via a Manganese‐Catalyzed Trifluoromethylazidation of Alkenes with CF3SO2Na and TMSN3. Issue 14 (23rd May 2018)

• Record Type: Journal Article
• Authors: Zhang, Yuecheng; Han, Xulin; Zhao, Jiquan; Qian, Zijian; Li, Tianmei; Tang, Yuqing; Zhang, Hong‐Yu
• Is Part Of: Advanced synthesis & catalysis. Volume 360:Issue 14(2018)
• Page Start: 2659
• Page End: 2667
• Publication Date: 2018-05-23
• Subjects: Trifluoromethylazidation -- Manganese-catalyzed -- Sodium trifluoromethanesulfinate -- Azidotrimethylsilane -- β-trifluoromethylated Alkyl Azides; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201800488
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: A convenient and efficient manganese‐catalyzed trifluoromethylazidation of alkenes has been developed by utilizing inexpensive and readily available CF3 SO2 Na under mild conditions. The various β‐trifluoromethylated alkyl azides were directly obtained from corresponding allyl, vinyl, chain terminal and internal alkenes, and easily further transformed into other CF3 ‐containing compounds. Abstract :